TABLE 1.
Relationship between ANXA2 expression and clinicopathologic factors in 51 lung cancer patients
| Characteristic | Low ANXA2 (n = 28) | High ANXA2 (n = 23) | p valuea |
|---|---|---|---|
| Age | 0.110 | ||
| Years (mean ± S.D.) | 65 ± 13 | 59 ± 10 | |
| Sex | 0.429 | ||
| Male | 11 | 11 | |
| Female | 17 | 12 | |
| Histological type | 0.758 | ||
| Adenocarcinoma | 22 | 16 | |
| Squamous cell carcinoma | 5 | 6 | |
| Large cell carcinoma | 1 | 1 | |
| Stageb | 0.006 | ||
| I | 20 | 6 | |
| II | 1 | 5 | |
| III | 6 | 7 | |
| IV | 1 | 5 | |
| Tumor status | 0.064 | ||
| T1-2 | 26 | 17 | |
| T3-4 | 2 | 6 | |
| Lymph node status | 0.047 | ||
| N0 | 22 | 12 | |
| N1–N3 | 6 | 11 | |
| Distal metastasis status | 0.045 | ||
| M0 | 27 | 18 | |
| M1 | 1 | 5 | |
| Tumor differentiation | 0.539 | ||
| Well | 9 | 5 | |
| Moderate | 12 | 8 | |
| Poor | 5 | 8 | |
| Unknown | 2 | 2 | |
| Recurrence status | 0.004 | ||
| No | 22 | 9 | |
| Yes | 6 | 14 | |
a p value for age was derived from a two-tailed Student's t test; other p values were derived with a two-tailed Pearson's χ2 test.
b The tumor stage, tumor status, lymph node status, distal metastasis status, and tumor differentiation were classified according to the international system for staging lung cancer.