Table 1.
Properties of CS-SA micelles, CS-SA/DOX micelles, and CS-SA/SiO2/DOX nanoparticles
| Material | dn (nm) | ξ (mV) | EE (%) | DL (%) |
|---|---|---|---|---|
| CS-SA | 117.5 ± 3.2 | 27.8 ± 2.9 | – | – |
| CS-SA/DOX | 28.9 ± 0.5 | 45.0 ± 2.2 | 93.18 | 4.45 |
| CS-SA/SiO2/DOX-4 | 56.3 ± 0.6 | 15.6 ± 4.1 | 93.45 | 4.46 |
| CS-SA/SiO2/DOX-8 | 75.2 ± 1.1 | 19.0 ± 3.5 | 89.09 | 4.26 |
| CS-SA/SiO2/DOX-16 | 36.0 ± 0.3 | 17.8 ± 2.4 | 85.36 | 4.09 |
Note: Data represent the mean ± standard deviation (n = 3).
Abbreviations: dn, number average diameter; ξ, zeta potential; CS, chitosan; DL, drug loading amount; DOX, doxorubicin; EE, encapsulation efficiency; SA, stearic acid.