Figure 1.

The kinetics of antibody production in Balb/c mice. Serum (100-fold dilution) of each of 6 Balb/c mice was obtained before immunization, and 3, 5, 8, 11, 14 weeks after the first immunization followed by the measurement. The representative results are given in fluorescent intensity units (FIU). IgG levels against peptide 4 and peptide 6, but not any others, became detectable at 3 weeks and reached a maximum at 5 weeks, followed by a decline thereafter until 11 weeks (^*P<0.05; 0 vs. 5 weeks). This analysis was done using Friedman’s test.