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Published in final edited form as: Clin Cancer Res. 2012 Aug 2;18(19):5412–5426. doi: 10.1158/1078-0432.CCR-12-1780

Fig. 5 — (A and B) Public data sets of galanin mRNA expression in CRC tumour (T) compared to Normal (N). Kaplan-Meier analysis, using the Log-rank (Mantel-Cox) statistical test, of (C) CRC GSE17536 dataset (probe ID: 214240_at) revealed that high galanin expression significantly correlated with decreased disease-free survival in stages I, II and III patients combined (HR=0.2143; 95% CI of ratio=0.06918 to 0.6641; P=0.0077; n=135), stage I only patients (P=0.0036) and stage II only patients (P=0.0025) but not stage III patients (NS) and (D) CRC GSE14333 dataset (probe ID: 214240_at) revealed a trend for high galanin and decreased disease-free survival in combined stages (P=0.098; n=246) and Duke’s A patients (P=0.06). There was a significant correlation between high galanin expression and decreased disease free survival in the Duke’s B patients (P=0.03).

Fig. 5 — (A and B) Public data sets of galanin mRNA expression in CRC tumour (T) compared to Normal (N). Kaplan-Meier analysis, using the Log-rank (Mantel-Cox) statistical test, of (C) CRC GSE17536 dataset (probe ID: 214240_at) revealed that high galanin expression significantly correlated with decreased disease-free survival in stages I, II and III patients combined (HR=0.2143; 95% CI of ratio=0.06918 to 0.6641; P=0.0077; n=135), stage I only patients (P=0.0036) and stage II only patients (P=0.0025) but not stage III patients (NS) and (D) CRC GSE14333 dataset (probe ID: 214240_at) revealed a trend for high galanin and decreased disease-free survival in combined stages (P=0.098; n=246) and Duke’s A patients (P=0.06). There was a significant correlation between high galanin expression and decreased disease free survival in the Duke’s B patients (P=0.03).