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Crystal structures of complexes between BaDHPS and pyridazine-derived inhibitors. a) Details of the interactions of compound 1 with key residues within the pterin binding site of BaDHPS. [21] b–f) Similar representations for compounds 19 (b), 23 (c), 25 (d)*, 17 (e), and 24 (f). *25 (d) binds in two conformations within the BaDHPS dimer and these are superimposed in the figure.
