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. 2012 Oct 3;7(10):e46708. doi: 10.1371/journal.pone.0046708

Table 1. Chromosomal genes showing highest transcript levels exclusively expressed by the pathogenic variant of the L. intracellularis isolate PHE/MN1-00 according to the putative biological function.

Locus Gene Description Log2 (RPKM)
Biological function
Cell division and macromolecule biosynthesis
LI0372 putative cell division protein FtsB 12.8
LI0844 tRNA and rRNA cytosine-C5-methylases 14.1
LI0962 rplW 50S ribosomal protein L23 13.5
Energy production and conversion
LI0442 hyaD processing of HyaA and HyaB proteins 10.9
LI1176 nitroreductase 11.1
Cellular processes and small molecule biosynthesis
LI0154 ribH riboflavin synthase beta-chain 12.6
LI0361 quinolinate synthetase 12.7
LI0735 ychB 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase 14.5
Membrane transport
LI0338 livH branched chain amino acid ABC transporter (permease) 12.5
LI0754 glnH amino acid ABC transporter substrate-binding protein 13.9
LI0995 oprM outer membrane efflux protein 12.1
Protein turnover and chaperones
LI0375 pcm protein-L-isoaspartate carboxylmethyltransferase 12.2
LI0225 smpB SsrA-binding protein 11.4
LI0618 ATPases with chaperone activity, ATP-binding subunit ClpA 11.4
Cell membrane and motility
LI0825 Lipid A core-O-antigen ligase and related enzymes 13.2
LI0947 cell wall-associated hydrolases 12.6
LI1141 cheW chemotaxis signal transduction protein 11.0
Adaptation and stress response
LI0035 fur Fe2+/Zn2+ uptake regulation proteins 11.8
LI0301 recO DNA repair protein RecO (recombination protein O) 13.0
LI0457 rpoN Sigma54-like protein 11.7
General predicted function
LI0140 glycosyltransferase 11.5
LI0246 hypA zinc finger protein 11.6
LI0880 sfsA DNA-binding protein, stimulates sugar fermentation 11.4
Hypothetical/Unknown function
LI0259 hypothetical protein 13.9
LI0917 hypothetical protein 12.9
LI1056 hypothetical protein 12.3