Table 3. Comparison of structural and functional features in human and mouse kidneys.
| Human | Mouse | |
| Body weight | 60 kg | 25 g |
| Kidney weight | 320 g | 320 mg |
| 5.3 g/kg BW | 12 g/kg BW | |
| Number of nephrons | 2×106 | 104 |
| 33/g BW | 400/g BW | |
| 6/mg KW | 31/mg KW | |
| GFR | 125 ml/min | 120 µl/min |
| 2.1 ml/min/kg BW | 4.8 ml/min/kg BW | |
| 391 µl/min/g KW | 375 µl/min/g KW | |
| Water intake and excretion | 1.5 l/day | 5 ml/day |
| Water reabsorption | 178.5 l/day | 168 ml/day |
| 0.56 l/day/g KW | 0.52 l/day/g KW | |
| Sodium intake and excretion | 5 g/day | 15 mg/day |
| Filtered sodium | 580 g/day | 556 mg/day |
| Sodium reabsorption | 575 g/day | 541 mg/day |
| 1.8 g/day/g KW | 1.7 g/day/g KW |
Data for body and kidney weights (BW & KW), glomerular filtration rate (GFR), number of nephrons (for both kidneys), urine volume (or water excretion) and sodium intake are commonly accepted values for humans. For mice, KW and GFR are from [10]; the GFR is calculated by multiplying the single nephron GFR of 10 nl/min [27] by the number of nephrons; water and sodium intake are unpublished data from our laboratory.