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. 2012 Oct 3;7(10):e46622. doi: 10.1371/journal.pone.0046622

Table 1. Summarized data of chimeric virus utilized in in vitro selections.

RT Origin RT Subtype RT fragment codons Vectors used Virus production methodology Virus name Replicates Amino acids differences between RT subtype B and C
NL4-3 B 35–225 ΔDNA polimerase RT HXB2 (11) recombination RTB 1 Reference
patient C 35–225 ΔDNA polimerase RT HXB2 (11) recombination RTC 1 V35T, E36A, T39D, K43R, S48T, V90F, Q102R, D121Y, K122E, D123N, S134I, I135T, C162S, E169K, K173N, Q174K, D177E, T200A, Q207E, R211K, F214L
NL4-3 B 25–554 ΔRT HXB2 (13) cloning RTB′ 6 Reference
C23 patient C 25–315 ΔNRT HXB2 (14) cloning RTC′ 6 V35T, E36A, T39D, K43R, S48T, Q102K, D121Y, K122E, C162S, K173N, Q174K, D177E, T200A, Q207E, R211K