Table 3. Random effects meta-regression analyses of Early and Delayed surgery time for overall mortality.
Characteristic | N. studies | N. participants | OR (95% CI) | p-value |
Continuous variables | ||||
Age (per 10 years) | 28 | 159772 | 0.97 (0.36 to 2.63) | 0.96 |
Female prevalence (per 10% more) | 32 | 187885 | 1.03 (0.92 to 1.16) | 0.55 |
Study year (per 10 years) | 34 | 191873 | 0.90 (0.7 to 1.18) | 0.46 |
Continuous time (per 24 hours) | 34 | 191873 | 0.22 (0.00077 to 63.62) | 0.59 |
Categorical variables | ||||
Study design | ||||
Prospective (reference) | 15 | 35112 | 1 | |
Retrospective | 20 | 156761 | 1.17 (0.82 to 1.66) | 0.36 |
Data source category | ||||
Clinical data (reference) | 24 | 46843 | 1 | |
Administrative data | 10 | 144053 | 1.05 (0.72 to 1.53) | 0.78 |
Study quality | ||||
8–9 stars (reference) | 18 | 149228 | 1 | |
1–7 stars | 17 | 42645 | 1.05 (0.73 to 1.5) | 0.79 |
Study location | ||||
Non-US study (reference) | 23 | 129179 | 1 | |
US study | 12 | 62694 | 0.94 (0.65 to 1.35) | 0.74 |
Early surgery time cut-off definition | ||||
<12 hours | 2 | 1500 | 1.2 (0.55 to 2.65) | 0.62 |
<24 hours (reference) | 16 | 97100 | 1 | |
<48 hours | 14 | 85378 | 0.97 (0.65 to 1.43) | 0.87 |
<96–120 hours | 3 | 7895 | 0.90 (0.46 to 1.78) | 0.77 |
Baseline risk | ||||
Risk<21% | 17 | 85826 | 1 | |
Risk>21% | 18 | 106047 | 0.86 (0.61 to 1.22) | 0.40 |