Table 3.

List of COL, MMP, and TIMP Genes that Were Significantly Differentially Methylated in Preeclamptic Omental Arteries

Symbol	Name	Gene ID	Mean β⁎		Δβ⁎	P value
			PE	NP
COL8A1	Collagen, type VIII, α 1	1295	0.078	0.054	0.024	0.02
COL9A3	Collagen, type IX, α 3	1299	0.536	0.480	0.056	0.03
COL19A1	Collagen, type XIX, α 1	1310	0.202	0.154	0.047	0.02
MMP1	Matrix metalloproteinase 1	4312	0.736	0.816	−0.080	0.02
MMP8	Matrix metalloproteinase 8	4317	0.807	0.882	−0.075	0.03
MMP12	Matrix metalloproteinase 12	4321	0.683	0.740	−0.057	0.01
MMP13	Matrix metalloproteinase 13	4322	0.745	0.830	−0.085	0.01
MMP16	Matrix metalloproteinase 16	4325	0.025	0.014	0.011	0.02
MMP21	Matrix metalloproteinase 21	118856	0.411	0.543	−0.132	0.02
MMP26	Matrix metalloproteinase 26	56547	0.762	0.862	−0.100	0.02
MMP27	Matrix metalloproteinase 27	64066	0.769	0.726	0.043	0.04
TIMP3	Tissue inhibitor of metalloproteinases 3	7078	0.437	0.338	0.098	0.02

NP, normal pregnant; PE, preeclamptic.

^⁎β indicates methylation values where 0 is no methylation and 1 is full methylation, and Δβ indicates the difference in methylation. Negative values indicate less methylation, and positive values indicate more methylation in PE arteries compared with NP arteries.