Table 4.

VMPFC and striatum region of interest analyses on gray matter volume.

	BA	Side	Voxels	peak Z	p-corrected	x (mm)	y (mm)	z (mm)
Controls > CUD
VMPFC: Medial OFC	11	L	347	3.5	0.029	−15 −3	36 39	−25 −28
CUD > Controls
None

Statistical threshold: p<0.005 uncorrected and p<0.05 family-wise error (FWE) corrected at voxel-level, k >5 voxels;

Striatum was defined anatomically with PickAtlas to correspond to the caudate, putamen, and pallidum;

Ventromedial prefrontal cortex (VMPFC) was defined as an 18-mm radius sphere centered on x=−2, y=32, z=−18 (from Ersche et al., 2011);

OFC: orbitofrontal cortex; L: left;

Coordinates in bold font are depicted in the figures.