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. Author manuscript; available in PMC: 2013 Oct 1.
Published in final edited form as: J Thromb Haemost. 2012 Oct;10(10):2108–2115. doi: 10.1111/j.1538-7836.2012.04890.x

FIGURE 4. Ni-Sepharose beads deplete plasma of specific contact pathway proteins.

FIGURE 4

PNP pre-adsorbed with Ni-Sepharose beads was used in PT and aPTT assays (the latter with the commercial aPTT reagent, STA-PTT-Automate 5). (A) Comparison of clotting times in Ni-Sepharose-treated plasma (solid bars) and untreated plasma (PNP; hatched bars). (B) aPTT assays were performed with 1:1 mixtures of Ni-Sepharose-treated plasma and either PNP or plasma deficient in the indicated clotting factor. Data are mean ± SEM (n = 3).