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. Author manuscript; available in PMC: 2013 Oct 1.

Published in final edited form as: Clin Cancer Res. 2012 Jul 23;18(19):5179–5187. doi: 10.1158/1078-0432.CCR-12-0726

Table 1.

True toxicity rates used to simulate the probability of a DLT at each dose level

	d₁	d₂	d₃	d₄	d₅	d₆
Scenario 1	0.10	0.17	0.22	0.30	0.45	0.50
Scenario 2	0.05	0.07	0.10	0.12	0.20	0.30
Scenario 3	0.05	0.20	0.35	0.45	0.50	0.55
Scenario 4	0.01	0.05	0.10	0.30	0.50	0.70
Scenario 5	0.05	0.15	0.20	0.25	0.30	0.50
Scenario 6	0.10	0.17	0.26	0.40	0.42	0.45