Figure 1.

(Color online) CPS Imaging of Gas Filled Silica Microshells. 100 μg/ml of gas filled 2 μm silica microshells were imaged in a thin-walled acoustically transparent chamber using CPS mode. (a) CPS image of microparticles at 0.39 MI. Each bright spot was a single imaging event; the white arrow points to a single imaging event. At low MI, the received signal intensity from each imaging event was low, resulting in dim images where the particle signal may be difficult to observe. (b) CPS image of microparticles at 1.9 MI. The large density of bright spots corresponded to a large number of particles being imaged. The received signal intensity was much stronger than at low MI, resulting in much brighter images. (c) CPS image of traditional microbubbles at a concentration of 10⁸ microbubbles/ml which closely correlated in particle count to 100 μg/ml of the silica microshells.