Table 2.
Group | N | Day | n | ||||||
---|---|---|---|---|---|---|---|---|---|
1 | 2 | 3 | 4 | 5 | 6 | 7 | |||
Number 1: estradiol + CP | 6 | — | — | — | — | — | — | — | 6 |
Number 2: estradiol + CP + vitamin E | 7 | — | — | — | — | — | — | — | 7 |
Number 3: estradiol + CP + vitamin C | 7 | — | — | — | — | 1 | 2 | 1 | 3 |
Number 4: estradiol + CP + losartan | 7 | — | — | — | — | 1 | 1 | 2 | 3 |
Number 5: CP + vehicle (positive control) | 5 | — | — | — | — | — | — | — | 5 |
Number 6: estradiol + vehicle (negative control) | 5 | — | — | — | — | — | — | — | 5 |
Number 7: vehicle (negative control) | 5 | — | — | — | — | — | — | — | 5 |
N: total number of animals at the beginning of experiment. All animals were ovariectomized, n: number of animals at the end of the experiment, CP: cisplatin. CP was administered at the beginning of the second week.