Skip to main content
. 2012 Aug 10;13(10):923–929. doi: 10.1038/embor.2012.119

Figure 3.

Figure 3

Meiotic DNA-damage and checkpoint activation are R-loop dependent. (A) Western analysis using anti-Rad53 and anti-β-actin antibodies for HPR1 and hpr1Δ homozygous diploids after transfer to sporulation media with and without RNase H1 overexpression. (B) Quantification of Rad52 foci for HPR1 and hpr1Δ homozygous diploids after transfer to sporulation media with and without RNase H1 overexpression. The means of cells with foci±s.d. are shown. (C) Fraction of cells that completed meiosis I (MI) and II (MII) in HPR1 and hpr1Δ homozygous diploids with and without RNase H1 overexpression. The means of cells±s.d. are shown.