Figure 5.

CD spectra of 25 μM Aβ(1–42) in a (A) Cu²⁺-free solution and (B) 25 μM Cu²⁺ solution incubated at pH 7.4 and 25 °C for different lengths of time. Panel (C) plots the ellipticity value at 197 nm (top two curves) and 217 nm (bottom two curves) against incubation time. The curves with open circles represent CD signals of Aβ(1–42) in the presence of Cu²⁺ and the curves with filled circles correspond to those in the absence of Cu²⁺.