Figure 1.

Behavioral responses in the elevated plus-maze of subchronic simvastatin treatment combined with fluoxetine (Flu) in rats: (A) percent time spent in open arm; (B) percent time spent in enclosed arm; (C) percent frequency of open arm entries; (D) percent frequency of enclosed arm entries; and (E) percent risk assessment time.

Notes: Bars represent the means for each group and the vertical lines represent the standard errors of the means. Newman–Keuls test showed that groups with asterisks are significantly different (n = 8; *P < 0.05; **P < 0.01; ***P < 0.001).