Table II.
n | Pdcd4 expression | Nuclear expression | Cytoplasmic expression | |||||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
|
|
|
||||||||||||||
0A | 1A | 2A | 3A | P-value | 1 | 2 | 3 | 4 | P-value | 1 | 2 | 3 | 4 | P-value | ||
T stage | ||||||||||||||||
1 | 2 | 0 | 1 | 1 | 0 | 0.443 | 1 | 0 | 0 | 1 | 0.018d | 1 | 0 | 1 | 0 | 0.903 |
2 | 21 | 3 | 8 | 9 | 1 | 5 | 2 | 10 | 4 | 13 | 4 | 3 | 1 | |||
3 | 80 | 8 | 20 | 46 | 6 | 17 | 14 | 9 | 40 | 45 | 20 | 13 | 2 | |||
4 | 8 | 0 | 4 | 1 | 0 | 1 | 2 | 1 | 1 | 4 | 1 | 0 | 0 | |||
N stage | ||||||||||||||||
N0 | 73 | 10 | 24 | 36 | 3 | 0.133 | 17 | 12 | 14 | 30 | 0.961 | 49 | 16 | 6 | 2 | 0.011d |
N1 | 35 | 1 | 9 | 21 | 4 | 7 | 6 | 16 | 16 | 14 | 9 | 11 | 1 | |||
M stage | ||||||||||||||||
M0 | 104 | 11 | 33 | 53 | 7 | 0.294 | 24 | 18 | 20 | 42 | 0.133 | 60 | 24 | 17 | 3 | 0.808 |
M1 | 4 | 0 | 0 | 4 | 0 | 0 | 0 | 0 | 4 | 3 | 1 | 0 | 0 | |||
Clinical stage | ||||||||||||||||
Highd | 72 | 10 | 24 | 35 | 3 | 0.114 | 17 | 12 | 14 | 29 | 0.906 | 49 | 15 | 6 | 2 | 0.009d |
Lowd | 36 | 1 | 9 | 22 | 4 | 7 | 6 | 6 | 17 | 14 | 10 | 11 | 1 | |||
Diff.1 | ||||||||||||||||
W/Ma | 88 | 11 | 26 | 46 | 5 | 0.359 | 22 | 14 | 15 | 37 | 0.724 | 54 | 17 | 15 | 2 | 0.440 |
Pb | 7 | 0 | 4 | 2 | 1 | 1 | 2 | 1 | 3 | 3 | 3 | 1 | 0 | |||
Mc | 13 | 0 | 3 | 9 | 1 | 1 | 2 | 4 | 6 | 6 | 5 | 1 | 1 | |||
Diff.2 | ||||||||||||||||
Non-M1 | 93 | 10 | 29 | 48 | 6 | 0.925 | 22 | 16 | 15 | 40 | 0.419 | 55 | 20 | 16 | 2 | 0.438 |
M2 | 15 | 1 | 4 | 9 | 1 | 2 | 2 | 5 | 6 | 9 | 5 | 1 | 1 |
Pdcd4 expression: 0A, negative staining (score 1–2); 1A, weak staining (score 3–4); 2A, intermediate staining (score 5–6); 3A, strong staining (score 7–8). N stage - N0, N1. Clinical stage: High, clinical stage I and II; Low, clinical stage I and II. Diff1: W/Ma, well to moderate differentiation; Pb, poor differentiation; Mc, mucinous carcinoma. Diff2: Non-M1, non-mucinous carcinoma; M2, mucinous carcinoma.
Statistically significant, p<0.05.