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. 2001 Jun 12;98(13):7170–7175. doi: 10.1073/pnas.121190898

Figure 4.

Figure 4

Lys C digestion of control and oxidized SHaPrP(29–231). SHaPrP(29–231) control and oxidized samples were digested with Lys C and reduced with 10 mM DTT at pH 9. Digests were analyzed by HPLC. Chromatograms represent the total ion current signal from the mass selective detector. Peptides are identified according to Table 1. (A) Control sample. (B) Sample treated with 1 μM CuCl2/25 mM. (C) Sample treated with 5 μM CuCl2/25 mM.