Figure 4 .

Deletions that rescue the eso1-G799D allele at nonpermissive temperature. Deletion of rox3, not3, and spt2 can partially rescue the growth defect at 37° of eso1-G799D mutation. (A) rox3, spt2, and not3 deletion can partially rescue the growth defect at 37° caused by eso1-G799D mutation. pds5 deletion was used as the control. None of these deletions can alleviate the hypersensitivity of the eso1-G799D mutant to 75Gy X-ray treatment. Deletions that rescue the eso1-G799D allele at nonpermissive temperature do not rescue TBZ sensitivity (B), but show partial rescue of lagging chromosomes (C).