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. 2012 Oct 4;7(10):e46849. doi: 10.1371/journal.pone.0046849

Table 2. Morphometric analysis of the myocardium in C57BL/6 LDLr−/− mice 6 weeks after saline injection or gene transfer with Adnull (controls), gene transfer with AdLDLr, and gene transfer with AdA-I.

Controls n = 13 AdLDLr n = 14 AdA-I n = 10
Cardiomyocyte cross-sectional area (µm2) 219±18 184±10 188±8
Cardiomyocyte density (number/mm2) 4490±300 5410±230* 4900±180
Capillary density (number/mm2) 5820±360 7460±330** 7190±410*
Capillary density/cardiomyocyte density 1.29±0.05 1.38±0.04 1.46±0.05*
Relative vascularity (µm−2) 0.00639±0.00045 0.00782±0.00043* 0.00794±0.00046*

Data are expressed as means ± SEM.

*

:p<0.05,

**

:p<0.01 for comparison versus Controls.