Table 2. Comparison of patient characteristics by IREG signature expression.
| IREG(+) | IREG(−) | P-value | |
| Breast cancer | |||
| Age (years) | 0.57 | ||
| <40 | 34 (23) | 29 (20) | |
| ≥40 | 114 (77) | 118 (80) | |
| Tumor size | 0.0016 | ||
| <T2 | 64 (43) | 91 (62) | |
| ≥T2 | 84 (57) | 56 (38) | |
| Lymph nodes | 0.82 | ||
| Uninvolved | 77 (52) | 74 (50) | |
| Involved | 71 (48) | 73 (50) | |
| ER expression | <0.001 | ||
| Negative | 58 (39) | 11 (7) | |
| Positive | 90 (61) | 136 (93) | |
| Tumor grade | <0.001 | ||
| 1, 2 | 63 (43) | 113 (77) | |
| 3 | 85 (57) | 34 (23) | |
| Colon cancer | |||
| Age (years) | 0.78 | ||
| <60 | 41 (35) | 38 (33) | |
| ≥60 | 75 (65) | 78 (67) | |
| Stage | 0.35 | ||
| I, II | 46 (40) | 54 (47) | |
| III, IV | 70 (60) | 62 (53) | |
| Tumor grade | 0.080 | ||
| 1, 2 | 90 (82) | 93 (90) | |
| 3 | 20 (18) | 10 (10) | |
| Glioma | |||
| Age (years) | 0.0050 | ||
| <55 | 25 (64) | 35 (92) | |
| ≥55 | 14 (36) | 3 (8) | |
| Lung cancer | |||
| Age (years) | 0.63 | ||
| <65 | 110 (50) | 104 (47) | |
| ≥65 | 111 (50) | 116 (53) | |
| Lymph nodes | 0.0076 | ||
| Uninvolved | 137 (62) | 162 (74) | |
| Involved | 83 (38) | 56 (26) | |
| Tumor size | 0.012 | ||
| <T3 | 193 (87) | 206 (95) | |
| ≥T3 | 28 (13) | 12 (5) | |
| Tumor grade | <0.001 | ||
| 1, 2 | 102 (47) | 63 (29) | |
| 3 | 117 (53) | 152 (71) |
Shown are the number and percentages of patients in each category. For each clinical or pathological variable, p-values were calculated by Fisher's exact test comparing IREG (+) and IREG (−) patients.