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. 2012 Oct 4;7(10):e47040. doi: 10.1371/journal.pone.0047040

Figure 5. IFN-induced up-regulation of DKK1 is dependent on STAT3 activation.

Figure 5

HepG2 (A) and Huh7 (B) cells were left untreated or treated with FLUD, S3I, or αDKK1 (DKK1 neutralizing antibody) alone or in combination with IFNα, IFNγ or IFNλ, respectively for 48 hrs. DKK1 levels were measured by ELISA. Data represent a minimum of three independent experiments. Asterisks denote p<0.05 in comparison to untreated samples.