Table 2. Distribution of CYP1A1 Ile462Val genotype among acute leukemia cases and controls included in the meta-analysis.
First Author | Year | Genotyping method | Cases | Controls | HWE (control) | |||||
Val/Val | Val/Ile | Ile/Ile | Val/Val | Val/Ile | Ile/Ile | Chi-squre | P | |||
Krajinovic | 1999 | PCR-RFLP | 1 | 11 | 158 | 0 | 24 | 275 | 0.523 | >0.05 |
Gao | 2003 | ASA | 10 | 44 | 24 | 11 | 59 | 42 | 2.226 | >0.05 |
D’Alo | 2004 | PCR-RFLP | 0 | 14 | 179 | 0 | 25 | 248 | 0.629 | >0.05 |
Gallegos-Arreola | 2004 | PCR | 22 | 65 | 49 | 8 | 59 | 69 | 1.010 | >0.05 |
Joseph | 2004 | PCR-RFLP | 10 | 34 | 74 | 3 | 20 | 95 | 2.168 | >0.05 |
Selvin | 2004 | Not determined | 5 | 39 | 131 | 4 | 44 | 127 | 0.007 | >0.05 |
Majumdar | 2008 | PCR-RFLP | 1 | 24 | 85 | 3 | 18 | 105 | 3.687 | >0.05 |
Lee | 2009 | SNaPshot | 6 | 39 | 60 | 9 | 65 | 85 | 0.567 | >0.05 |
Yamaguti | 2009 | PCR-RFLP | 4 | 54 | 75 | 2 | 39 | 92 | 0.891 | >0.05 |
Yamaguti | 2010 | PCR-RFLP | 3 | 36 | 60 | 3 | 29 | 67 | 0.004 | >0.05 |
Razmkhah (Adult) | 2011 | PCR-RFLP | 1 | 38 | 66 | 1 | 18 | 76 | 0.003 | >0.05 |
Razmkhah (Childhood) | 2011 | PCR-RFLP | 0 | 13 | 72 | 0 | 14 | 80 | 0.609 | >0.05 |
Swinney | 2011 | Golden gate assay | 14 | 40 | 188 | 18 | 118 | 505 | 10.693 | <0.05 |
Kim | 2012 | PCR-RFLP | 17 | 173 | 225 | 87 | 654 | 959 | 3.311 | >0.05 |