Table 1. Modafinil treatment prevents METH-induced striatal amoeboid-shaped microglial differentiation.
Treatment | Time after treatment | |
48 h | 6 d | |
VEH | 0 | 0 |
MOD | 0.25±0.25 | 0 |
METH | 14.25±8.17* | 0.28±0.18 |
M+M | 0 | 0 |
ILB4-positive cell number per mice with amoeboid-shaped morphology was estimated.
Values are expressed as mean number of amoeboid microglia ± SEM (n = 4−8). Kruskal Wallis ANOVA on ranks was performed to draw comparisons between the different groups: *p<0.05.