Table 3.
Correlations between improvements in changes from baseline in quality of life domains, workplace productivity and treatment satisfaction vs. Week 12 global improvement of IBS symptoms. Results reported were all statistically significant and moderately correlated
| Outcome measure | Spearman coefficient* | P-value |
|---|---|---|
| Quality of life domain | ||
| Emotional | 0.53 | <0.0001 |
| Mental health | 0.44 | <0.0001 |
| Sleep | 0.38 | <0.0001 |
| Energy | 0.51 | <0.0001 |
| Physical functioning | 0.40 | <0.0001 |
| Food/diet | 0.51 | <0.0001 |
| Social functioning | 0.57 | <0.0001 |
| Physical role | 0.53 | <0.0001 |
| Sexual relations | 0.45 | <0.0001 |
| Lost workplace productivity | −0.34 | <0.0001 |
| Treatment satisfaction | −0.56 | <0.0001 |
GIS, global improvement scale; IBS, irritable bowel syndrome; IBSQOL, irritable bowel syndrome quality of life.
*
Responder status and ratings for GIS at Week 12 were correlated with IBSQOL, workplace productivity and treatment satisfaction parameters using Spearman's rank correlation coefficient.