Table 1.
Univariate statistical analysis comparing patients with and without development of intracranial hemorrhage (ICH)
| With ICH (n = 19) | Without ICH (n = 140) | p value | |
|---|---|---|---|
| Age (mean ± SD years) | 80.1 ± 9.2 | 74.8 ± 11.8 | 0.060 |
| Sex (male) | 11 (58%) | 77 (55%) | 0.664 |
| IV-tPA | 8 (42%) | 28 (20%) | 0.041 |
| Hypertension | 9 (47%) | 100 (71%) | 0.062 |
| Diabetes mellitus | 5 (26%) | 34 (24%) | 0.784 |
| Dyslipidemia | 3 (16%) | 22 (16%) | 1.000 |
| Atrial fibrillation | 12 (63%) | 62 (44%) | 0.145 |
| Previous ischemic heart disease | 2 (11%) | 13 (9%) | 0.695 |
| Previous cerebrovascular disease | 3 (16%) | 34 (24%) | 0.567 |
| Antiplatelet agent use | 3 (16%) | 29 (21%) | 0.767 |
| Anticoagulant use | 2 (11%) | 26 (19%) | 0.531 |
| Platelet count on admission (×104/μl) | 18.7 ± 5.3 | 19.6 ± 5.3 | 0.522 |
| Systolic blood pressure on admission (mmHg) | 156.4 ± 23.4 | 161.3 ± 33.2 | 0.532 |
| Diastolic blood pressure on admission (mmHg) | 77.1 ± 20.0 | 86.8 ± 21.1 | 0.058 |
| Glucose on admission (mg/dl) | 144.6 ± 68.2 | 138.2 ± 51.3 | 0.626 |
| NIHSS score on admission, median (IQR) | 23(15–25) | 12.5 (5–25) | 0.010 |
| CT-ASPECTS, median (IQR) | 7 (5–10) | 10 (7–10) | 0.008 |
| DWI-ASPECTS, median (IQR) | 6 (3–8) | 9 (6–10) | 0.001 |
| ASPECTS+W, median (IQR) | 6 (3–8) | 9 (6–10) | 0.001 |
| DWI-W lesions | 14 (74%) | 66 (47%) | 0.048 |
| Stroke subtype (TOAST classification) | 0.355 | ||
| Cardioembolism | 14 (74%) | 77 (55%) | |
| Large artery atherosclerosis | 4 (21%) | 26 (19%) | |
| Small vessel occlusion | 0 | 15 (11%) | |
| Other causes | 0 | 1 (15) | |
| Undetermined | 1 (5%) | 21 (15%) | |
| Presence of ICA/M1 proximal occlusion | 13(68%) | 44(32%) | 0.004 |
IQR interquartile range ICH both symptomatic and asymptomatic ICH