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. 2012 Feb 17;259(10):2045–2052. doi: 10.1007/s00415-012-6446-1

Table 2.

Multivariate analysis for development of intracranial hemorrhage

OR 95% CI p value
Model 1 (CT-ASPECTS)
 Age (per year) 1.05 0.98–1.13 0.180
 Sex (female) 0.53 0.15–1.68 0.292
 IV–tPA 6.01 1.58–25.60 0.010
 NIHSS score on admission (per point increase) 1.02 0.95–1.10 0.549
 Presence of hypertension 2.28 0.75–7.16 0.147
 Diastolic blood pressure on admission (per mmHg increase) 0.98 0.95–1.01 0.143
 CT-ASPECTS (per point increase) 0.82 0.64–1.03 0.094
 Presence of ICA/M1 proximal occlusion 2.74 0.80–10.33 0.118
Model 2 (DWI-ASPECTS)
 Age (per year) 1.06 0.99–1.14 0.113
 Sex (female) 0.53 0.15–1.71 0.300
 IV-tPA 8.88 2.01–46.49 0.005
 NIHSS score on admission (per point increase) 1.00 0.92–1.09 0.942
 Presence of hypertension 2.11 0.68–6.73 0.198
 Diastolic blood pressure on admission (per mmHg increase) 0.98 0.95–1.01 0.222
 Presence of ICA/M1 proximal occlusion 1.96 0.53–7.72 0.316
 DWI-ASPECTS (per point increase) 0.76 0.57–1.00 0.056
 Presence of DWI-W lesion 0.68 0.17–2.44 0.555
Model 3 (ASPECTS+W)
 Age (per year) 1.06 0.99–1.14 0.107
 Sex (female) 0.53 0.15–1.71 0.302
 IV-tPA 9.13 2.15–46.21 0.004
 NIHSS score on admission (per point increase) 1.00 0.92–1.09 0.949
 Presence of hypertension 2.09 0.67–6.63 0.201
 Diastolic blood pressure on admission (per mmHg increase) 0.98 0.95–1.01 0.225
 ASPECTS+W (per point increase) 0.75 0.58–0.96 0.027
 Presence of ICA/M1 proximal occlusion 1.97 0.54–7.75 0.313

OR odds ratio, CI confidence interval