Fig. 1.

Two patterns were identified regarding the changes of glutamate levels over the monitoring period. In Pattern 1 (left), the glutamate levels tend to normalize over time. Two trends represent subgroups of this pattern: in the first, levels are initially low and remain low; in the second, they are initially high but decrease over time. In Pattern 2 (right), the glutamate levels tend to increase over time or remain abnormally elevated. Three trends are identified as subgroups of this pattern: in the first, levels are initially low but increase over time; in the second, they are initially high, and although they decrease over time, they remain abnormally elevated; and in the third, they are initially high and continue to increase for several days before decreasing.