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. Author manuscript; available in PMC: 2013 Sep 4.
Published in final edited form as: Circulation. 2012 Jul 31;126(10):1206–1216. doi: 10.1161/CIRCULATIONAHA.111.089409

Figure 4.

Figure 4

The 39 individuals who died had higher extracellular volume fraction (ECV) in myocardium without MI. Frequency histograms of ECV in 793 consecutive patients referred for clinical CMR exams are shown according to whether they survived (panel A) or died (panel B). Based on 9 healthy volunteers without evident cardiovascular disease or risk factors whose ECV ranged 21.7%–26.2%, an ECV > 28.5% was estimated to be “abnormally elevated” (i.e., beyond the 99th percentile assuming a normal distribution) represented by the black vertical lines (Panel A). Among surviving individuals, a considerable burden of extracellular matrix expansion reflected by ECV appears evident for a significant proportion, suggesting risk for adverse outcomes.