Table 2.
Fathers’ Demographic, Exposure, and Interview Characteristics: Cases Without Controls, Cases With Controls, and Controls From a Case-control Study of Retinoblastoma Using Friend Controls, United States, 2002 – 2007.
Exposure/characteristica | Cases without controls N=62b | Cases with controls N=137b | Controls N=247b | |||
---|---|---|---|---|---|---|
# | % | # | % | # | % | |
Race/ethnicityc | ||||||
White, non-Hispanic | 23 | 37 | 104 | 76 | 202 | 82 |
Black, non-Hispanic | 13 | 21 | 17 | 12 | 19 | 8 |
Hispanic | 15 | 24 | 10 | 7 | 18 | 7 |
Other | 11 | 18 | 6 | 4 | 8 | 3 |
Education | ||||||
Less than high school | 14 | 23 | 5 | 4 | 13 | 5 |
High school graduate | 18 | 29 | 36 | 26 | 45 | 18 |
Some post high school | 17 | 27 | 33 | 24 | 51 | 21 |
College graduate | 8 | 13 | 39 | 29 | 88 | 36 |
Graduate/professional school | 5 | 8 | 23 | 17 | 50 | 20 |
Income | ||||||
< $25,000 | 18 | 37 | 8 | 7 | 21 | 10 |
$25 – 35,000 | 8 | 17 | 13 | 11 | 19 | 9 |
$35 – 50,000 | 5 | 10 | 26 | 21 | 37 | 17 |
$50 – 75,000 | 11 | 23 | 28 | 23 | 50 | 23 |
> $75,000 | 6 | 12 | 47 | 39 | 86 | 40 |
Age at child’s birth | ||||||
< 25 | 8 | 13 | 11 | 8 | 18 | 7 |
25 – 29 | 19 | 31 | 30 | 22 | 71 | 29 |
30 – 34 | 13 | 21 | 43 | 31 | 82 | 33 |
35 – 39 | 16 | 26 | 40 | 29 | 53 | 21 |
40 + | 5 | 8 | 13 | 9 | 23 | 9 |
Marital status at interview | ||||||
Married | 44 | 72 | 125 | 91 | 229 | 93 |
Not married | 17 | 28 | 12 | 9 | 16 | 7 |
Interviewed by proxy | ||||||
Yes | 17 | 27 | 16 | 12 | 43 | 17 |
No | 45 | 73 | 121 | 88 | 204 | 83 |
Smoked | ||||||
Yes | 34 | 55 | 38 | 28 | 55 | 22 |
No | 28 | 45 | 99 | 72 | 192 | 78 |
# cigarettes/day | ||||||
None | 28 | 47 | 99 | 72 | 192 | 78 |
1–10/day | 18 | 30 | 19 | 14 | 31 | 13 |
11–50/day | 14 | 23 | 19 | 14 | 24 | 10 |
Binge drinkingd | ||||||
< 1time/month | 47 | 80 | 119 | 87 | 207 | 84 |
≥ 1time/month | 12 | 20 | 18 | 13 | 40 | 16 |
Multivitamin use | ||||||
Yes | 17 | 28 | 55 | 40 | 83 | 34 |
No | 44 | 72 | 82 | 60 | 164 | 66 |
Vitamin C supplement use | ||||||
Yes | 8 | 15 | 38 | 31 | 49 | 22 |
No | 44 | 85 | 84 | 69 | 174 | 78 |
Apple consumption | ||||||
< 1 serving/week | 33 | 63 | 75 | 58 | 100 | 43 |
≥ 1 serving/week | 19 | 36 | 54 | 42 | 130 | 57 |
Cured meat intake | ||||||
< 2 servings/week | 28 | 54 | 47 | 39 | 116 | 52 |
≥ 2 servings/week | 24 | 46 | 75 | 61 | 107 | 48 |
Body mass index | ||||||
< 25 | 18 | 35 | 35 | 29 | 76 | 34 |
≥ 25 | 33 | 65 | 87 | 71 | 147 | 66 |
History of lower GIe series | ||||||
Yes | 3 | 6 | 11 | 9 | 8 | 4 |
No | 49 | 94 | 111 | 91 | 215 | 96 |
Exposures/characteristics pertain to the father in the year before the index pregnancy except that the time period for history of lower GI series is any time prior to the index child’s conception.
Missing data explain the differing number of total subjects among exposures/characteristics. A small proportion of fathers completed shorter questionnaires that did included a shortened supplement section and no diet or medical radiation section. Thus, for vitamin C supplement use, cured meat intake, apple consumption, body mass index, and history of lower GI series, the maximum numbers are 52 cases without controls, 122 cases with controls, and 223 controls.
Cases with and without controls differ significantly in race/ethnicity (P<0.001), educational level (P <0.001), income (P <0.001), marital status (P =0.001), father interviewed by proxy (P =0.008), smoked (P <0.001), and # cigarettes/day (P=0.002).
Binge drinking was defined as consuming 6 or more drinks on one occasion
Gastrointestinal