Official websites use .gov
A
.gov website belongs to an official
government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you've safely
connected to the .gov website. Share sensitive
information only on official, secure websites.
Roles of TLR4-TRIF and caspase-11 during C. rodentium infection in vivo. A, survival of WT, Tlr4−/−, Myd88−/−, Trif−/−, and Myd88−/−Trif−/− mice infected with 1 × 1010 C. rodentium by oral gavage. B and C, bacterial burden in fecal pellets of infected mice determined at day 7 after infection. D, working model for TLR4-/TRIF-mediated regulation of caspase-11 expression and noncanonical inflammasome activation in C. rodentium- and E. coli-infected macrophages.
