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Specificity of the M-T hook for the thermostability and anti-HIV activity
| Peptide | Tm | IC50 data |
|
|---|---|---|---|
| HIV-1 entry | 6-HB formation | ||
| °C | nm | μm | |
| C34 | 65.2 | 1.5 ± 0.1 | 2.3 ± 0.1 |
| MT-C34 | 75 | 0.4 ± 0.0 | 0.4 ± 0.0 |
| AA-C34 | 65.3 | 1.3 ± 0.1 | 3.4 ± 0.3 |
| TM-C34 | 65.2 | 1.4 ± 0.2 | 3.8 ± 0.2 |
