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. 2012 Jul 9;13:160. doi: 10.1186/1471-2105-13-160

Table 1.

Comparison of ParticleCall with differentNp

Method Np error rate base-calling time (min)  
ParticleCall (via MCEM)
400
0.0126
46
 
 
800
0.0124
88
 
 
1200
0.0124
130
 
ParticleCall (via PFEM)
400
0.0128
46
 
 
800
0.0125
91
 
 
1200
0.0125
133
 
Rao-Blackwellized ParticleCall (via MCEM)
100
0.0128
103
 
 
200
0.0125
190
 
 
300
0.0124
287
 
  400 0.0124 386  

ParticleCall is run using parameters obtained via the MCEM parameter estimation scheme as well as via the PFEM parameter estimation algorithm proposed in this paper. Rao-Blackwellized ParticleCall is run using parameters via the MCEM parameter estimation scheme.