Table 3.
Abnormalities in AMI rats andSp6-deficient mice
| Organ | Category |
AMI rats this study, [42,58] |
Sp6-deficient mice [50,51,57] |
|---|---|---|---|
| Teeth |
Number |
Normal |
Excess (hyperdontia) |
| |
Enamel |
Thin, calcified |
Absence or thin |
| |
Ameloblasts |
|
|
| |
- Nuclear |
Polarized |
Not well-polarized |
| |
-Tome’s process |
No |
Atypical |
| |
-Morphological differentiation |
Early regression |
Defect |
| Hair |
|
Normal |
Short, alopecia, no fur |
| Whisker |
Pups (at birth) |
Curly |
Rare, short, curly, alopecia |
| |
Adult |
Feeble |
Delayed appearance |
| Digits | Normal | Syndactyly, oligodactyly |