Table 1.

Characteristics of study subjects by the study drug on enrolment

Characteristic	Artemisinin- naphthoquine(AN)	Dihydroartemisinin- piperaquine(DHP)	P	Overall
Number of subjects	201	200		401
Age:mean ± SD (range) years	27.6 ± 10.8 (15–69)	26.2 ± 9.2 (15–67)	0.18	26.9 ± 10.0 (15–69)
Body weight: mean ± SD (range) kgs	58.7 ± 8.5 (36–81)	58.5 ± 8.5 (37–85)	0.86	58.6 ± 8.5 (36–85)
Axillary temperature: mean ± SD (range) °C	37.9 ± 1.0 (36–40.3)	37.9 ± 1.1 (35–40.2)	0.84	37.9 ± 1.1 (35–40.3)
Blood Pressure Systole: mean ± SD (range) mmHg	113 ± 13 (90–150)	114 ± 13 (80–170)	0.44	113 ± 13 (80–170)
Diastole: mean ± SD (range) mmHg	72 ± 9 (50–92)	73 ± 9 (40–120)	0.39	72 ± 9 (40–120)
Heart rate: mean ± SD (range) per min	86 ± 13 (52–126)	87 ± 13 (56–126)	0.59	86 ± 13 (52–126)
Respiration rate: mean ± SD (range) per min	20 ± 3 (16–36)	20 ± 3 (16–32)	0.51	20 ± 3.0 (16–36)
Sex: male:female (%)	181:20 (90:10)	170:30 (85:15)	0.17	351:50 (87.5:12.5)
History of fever in the last 24 hours (%)	195 (97.0)	199 (99.5)	0.12	394 (98.3)
Study subject with T.axillary ≥37.5°C (%)	114 (56.7)	109 (54.5)	0.73	223 (55.6)
History of experience malaria in the last year (%)	160 (79.6)	159 (79.5)	1.00	319 (79.6)
Frequency of malaria in the last year: mean ± SD (range) times	2.6 ± 2.3 (1–20)	2.4 ± 1.6 (1–12)	0.53	2.7 ± 3 (1–20)
History of taken antimalarial drugs in the last 4 weeks (%)	55 (27.4)	57 (28.5)	0.89	112 (27.9)