Table 2.

Comparison of available studies in the literature

Study	Irradiated liver metastases (n)	Nominal total dose/single dose (Gy)	BED2 (Gy)	Lesion size (ccm)	Median FU (months)	1-year LC rate (%)
Katz et al., 2007 [21]	69	30-55/2-6	40-73*	0.1-950*	14.5	76
McCammon et al., 2009 [5]	81	3 dose levels:	3 levels*:	2.8-370	8.2
		1.) < 36/12	1.) 39			1.) 40
		2.) 36-54/12-18	2.) 39-58			2.) 88
		3.) 54/18	3.) 58			3.) 100
Milano et al., 2008 [22]	121	10-20/10-20	16-50	0.2-422	Not stated	57
Goodmann et al., 2010 [23]	40	18-30/18-30	42-100*	0.8-146	17	77
Iwata et al., 2010 [24]	12	50-55/5-5.5	62-71*	0.9-22*	14.5	86
Rusthoven et al., 2009 [25]	63	36-60/12-20	66-150*	<113*	16	95
Lee et al., 2009 [26]	68	42-60/7-10	59-100*	1.19-3000	10.8	71
Current series JBH et al.	22	24-60/24-12	44-150	11-419	12	57

BED2 and PTV volumes were calculated by JBH et al. (V = 4/3πr³; median/range) in the cases marked with *.