Table 1.
Levels of inflammatory markers overall and by selected subgroups
| |
|
hs-CRP (μg/mL) |
IL-1β (pg/mL) |
IL-6 (pg/mL) |
TNF-α (pg/mL) |
||||
|---|---|---|---|---|---|---|---|---|---|
| Subjects [n] | N | Median (P25-P75) | N | Median (P25-P75) | N | Median (P25-P75) | N | Median (P25-P75) | |
|
All subjects |
6183 |
6171 |
1.30(0.60-2.70) |
6083 |
0.39(0.10-1.74) |
6077 |
1.32(0.58-3.21) |
6077 |
2.87(1.79-4.50) |
|
Sex | |||||||||
| Female |
3251(52.6) |
3247 |
1.30(0.60-2.90) |
3200 |
0.45(0.10-1.93) |
3197 |
1.21(0.53-2.93) |
3196 |
2.73(1.71-4.38) |
| Male |
2932(47.4) |
2924 |
1.20(0.60-2.60) |
2883 |
0.34(0.10-1.52) |
2880 |
1.46(0.65-3.53) |
2881 |
3.03(1.89-4.62) |
| p-value |
|
|
0.01 |
|
<0.01 |
|
<0.01 |
|
<0.01 |
|
Age (Years) | |||||||||
| <55 |
3506(56.7) |
3500 |
1.00(0.50-2.40) |
3447 |
0.49(0.10-2.13) |
3444 |
1.20(0.52-3.16) |
3442 |
2.69(1.68-4.26) |
| > = 55 |
2677(43.3) |
2671 |
1.60(0.80-3.20) |
2636 |
0.29(0.10-1.32) |
2633 |
1.46(0.68-3.27) |
2635 |
3.13(1.99-4.82) |
| p-value |
|
|
<0.01 |
|
<0.01 |
|
<0.01 |
|
<0.01 |
|
BMI | |||||||||
| <25 |
2970(48.0) |
2963 |
0.80(0.40-1.70) |
2923 |
0.46(0.10-1.99) |
2921 |
1.15(0.49-3.10) |
2920 |
2.68(1.68-4.20) |
| > = 25 |
3213(52.0) |
3208 |
1.90(0.90-3.80) |
3160 |
0.35(0.10-1.52) |
3156 |
1.46(0.69-3.34) |
3157 |
3.09(1.90-4.79) |
| p-value |
|
|
<0.01 |
|
<0.01 |
|
<0.01 |
|
<0.01 |
|
Smoking | |||||||||
| No |
4510(72.9) |
4506 |
1.20(0.60-2.70) |
4452 |
0.39(0.10-1.68) |
4449 |
1.22(0.54-3.00) |
4448 |
2.84(1.78-4.46) |
| Yes |
1673(27.1) |
1665 |
1.40(0.70-2.90) |
1631 |
0.42(0.10-1.99) |
1628 |
1.57(0.75-3.76) |
1629 |
2.99(1.86-4.78) |
| p-value |
|
|
<0.01 |
|
0.07 |
|
<0.01 |
|
<0.01 |
|
Diabetes | |||||||||
| No |
5764(93.2) |
5764 |
1.20(0.60-2.60) |
5680 |
0.41(0.10-1.79) |
5675 |
1.29(0.57-3.16) |
5674 |
2.84(1.78-4.46) |
| Yes |
407(6.8) |
407 |
2.10(1.00-4.50) |
402 |
0.15(0.10-0.97) |
401 |
1.87(0.90-3.78) |
402 |
3.52(2.20-5.35) |
| p-value |
|
|
<0.01 |
|
<0.01 |
|
<0.01 |
|
<0.01 |
|
Hypertension | |||||||||
| No |
3960(47.9) |
3953 |
1.10(0.50-2.30) |
3895 |
0.46(0.10-1.95) |
3893 |
1.19(0.52-3.08) |
3891 |
2.72(1.69-4.29) |
| Yes |
2223(52.1) |
2218 |
1.80(0.90-3.60) |
2188 |
0.30(0.10-1.42) |
2184 |
1.54(0.71-3.45) |
2186 |
3.17(2.04-4.92) |
| p-value |
|
|
<0.01 |
|
<0.01 |
|
<0.01 |
|
<0.01 |
|
Alcohol | |||||||||
| No |
4613(74.6) |
4606 |
1.20(0.60-2.70) |
4541 |
0.42(0.10-1.83) |
4536 |
1.27(0.55-3.10) |
4536 |
2.84(1.78-4.50) |
| Yes |
1567(25.4) |
1567 |
1.40(0.70-2.70) |
1540 |
0.34(0.10-1.58) |
1539 |
1.48(0.66-3.54) |
1539 |
2.96(1.84-4.60) |
| p-value | <0.01 | <0.01 | <0.01 | 0.11 | |||||
Note: by Wilcoxon rank sum test.