Table 1.

Statistics for protein-DNA datasets supplied with DREM 2.0

Species	#TFs	#genes	Protein-DNA interactions	Type	Reference
S. cerevisiae	205	6,230	22,167	ChIP-Chip, conservation	[34,35]
E.coli	124	1,763	3,520	curated + computational	[26]
D. melanogaster	77	12,504	158,558	ChIP-Chip,ChIP-Seq	[8]
M. musculus	336	16,641	468,319	computational prediction,supplement	[36]
H. sapiens	127	19,755	954,377	ChIP-Seq	[37]
H. sapiens	349	17,848	514,925	computational prediction	[36]
A. thaliana	68	8,132	11,354	diverse experimental evidence	[38]

Number of protein-DNA interactions for TFs and target genes for the six supplied species H. sapiens, A. thaliana, and M. musculus, S. cerevisiae, and E.coli since DREM 2.0. Higher-confidence subsets of these interactions are also provided for some species. More details can be found in Additional file 2.