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MMP-2 ELISA analysis of conditioned media from tsc2ang1 cells treated with either rapamycin, imatinib or the combination for 24 hours resulted in a decrease in the amount of MMP-2 produced in comparison to controls. MMP-2 levels in the tsc2ang1 cells treated with imatinib only and imatinib + rapamycin were significantly decreased compared to that of controls.
