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. Author manuscript; available in PMC: 2013 Oct 2.
Published in final edited form as: Biochemistry. 2012 Sep 21;51(39):7676–7684. doi: 10.1021/bi3009888

Figure 6.

Figure 6

Membrane fragmentation induced by IAPP. 15 µM IAPP was incubated with 1 mg/ml large unilamellar vesicles before fragmented membranes were separated by centrifugation at 14,000 rpm. Lipid concentrations were measured by the Stewart assay. All experiments were performed in 10 mM phosphate buffer, 100 mM NaCl, pH 7.4. Results are the average of three experiments, error bars indicate the standard error of measurement. The fragmentation of membranes containing PE is significantly higher than those without.