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SHIV162P3envdiversity in PrEP breakthroughs and untreated control macaques
| Mean nucleotide diversity (%) (range) | |||
|---|---|---|---|
| |
PrEP |
Controls |
P value |
| Peak |
0.027 (0.015-0.05) |
0.053 (0.02-0.10) |
P < 0.0001 |
| Week 17* | 0.14 (0.04-0.26) | 0.53 (0.08-0.92) | P < 0.0001 |
* Sequences were obtained an average of 17 weeks post peak viremia for the 4 PrEP breakthroughs (15, 16, 18, and 18 weeks) and the 5 untreated controls (12, 16, 18, 19, and 20 weeks).
