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Hepatic expression of Cd59a increases with age independently of Cfh. qRT-PCR analyze of selected complement genes in the liver revealed increased expression of Cd59a with age in both WT and Cfh−/− mice. The classical components C1qc and Serping1 also increased with age (only tendency in Cfh−/− mice), while there was no differential expression of Cfb or C3; 5 to 6 mice in each group. Error bars represent SEM. *P < 0.05. **P < 0.01.
