Table 2.
ORIGINAL INTERACTIONS | ADDED INTERACTIONS | ||
---|---|---|---|
TGFα→MEK1 | 12 | IL1α→MEK1 | 9 |
IKK→IKB | 12 | IL1α→ERK1 | 4 |
IL1α→JNK | 12 | P38→MEK1 | 2 |
IL1α→ p38 | 12 | AKT→ JNK | 2 |
P13K→AKT | 11 | IKK→ERK1/2 | 2 |
p38→HSP27 | 11 | MEK1→AKT | 1 |
MEK1→ERK1/2 | 10 | JNK→AKT | 1 |
TGFα→PI3K | 7 | JNK→IKB | 1 |
IGF1→MEK1 | 7 | p38→AKT | 1 |
TNFα→p38 | 7 | IKB→HSP27 | 1 |
IL1A→IKK | 7 | JNK→MEK1 | 1 |
TGFα→p38 | 7 | ERK1/2→MEK1 | 1 |
IGF1→PI3K | 7 | IKK→PI3K | 1 |
TNFα→IKK | 6 | IKB→ERK1/2 | 1 |
IL1α→HSP27 | 6 | IKK→HSP27 | 1 |
AKT→MEK1 | 6 | HSP27→ERK1/2 | 1 |
TNFα→JNK | 5 | MEK1→JNK | 1 |
TNFα→PI3K | 4 | IKB→AKT | 1 |
AKT→IKK | 3 | ||
TGFα→JNK | 3 | ||
PI3K→MEK1 | 3 | ||
IGF1→p38 | 3 | ||
ERK1/2→HSP27 | 2 | ||
TGFα→IKK | 2 | ||
TNFα→HSP27 | 1 |