Table 3.
mRNA expression level of cDNA-AFLP candidate genes – cachexia vs. no cachexia
| Gene description | Fold change | Gene description | Fold change |
|---|---|---|---|
| α1-antitrypsin (serpin) |
18.61 |
fibrinogen α |
6.65 |
| α2-macroglobulin |
4.77 |
forkhead transcription factor FOXO1A |
5.22 |
| ankyrin |
0.41 |
immediate early response 5 (IER-5) |
7.72 |
| archvillin |
22.04 |
karyopherin alpha (importin 5) |
0.54 |
| breast cancer-associated protein |
9.47 |
mt translational release factor 1 (MTRF 1) |
9,68 |
| calsequestrin 1 |
22.03 |
myocyte enhancer factor 2 (MEF2) |
13.77 |
| cardiomyopathy associated protein 5 |
15.4 |
myosin regulatory light chain (MYLC) |
5.63 |
| cofilin 2 |
16.72 |
myosin heavy chain 7 (MYH7) |
4.54 |
| cyclin-dependent kinase inhibitor 1A (p21) |
6.54 |
NK transcript (IL-32) |
6.1 |
| bHLH transcription factor DEC1 |
3.46 |
synaptopodin (SYNPO) |
1.79 |
| bHLH transcription factor DEC2 |
2.3 |
titin |
4.19 |
| bHLH transcription factor HES1 |
5.28 |
vimentin |
2.39 |
| early growth response 1 (Egr-1) | 61.14 | vinculin | 2.68 |