Table 1.
Characteristics of the studied population
| Whole population (n = 64) | Patients with SS genotype (n = 41) | Patients with non- SS genotype (n = 23) | p value * SS vs non-SS | |
|---|---|---|---|---|
| |
(n = 64) |
(n = 41) |
(n = 23) |
|
|
Sex ratio (M/F), (M%) |
16/48 (25.0%) |
11/30 (27%) |
5/18 (22%) |
0.22 |
|
Age, years |
27.5 [18–67.5] |
26.8 [18–49.5] |
31.7 [18–67.5] |
0.03 |
|
Ethnical origin |
|
|
|
0.74 |
|
Sub Saharian Africa |
48 (75%) |
32 (78.1%) |
16 (69.6%) |
|
|
French West Indies |
10 (15.6%) |
6 (14.6%) |
4 (17.4%) |
|
|
Maghreb |
2 (3.1%) |
1 (2.4%) |
1 (4.3%) |
|
|
Other |
4 (6.3%) |
2 (4.9%) |
2 (8.7%) |
|
|
Height, m |
1.67 [1.48-1.83] |
1.68 [1.53-1.83] |
1.66 [1.48-1.78] |
0.27 |
|
Weight, kg |
63 [43.5-90] |
61.5 [43.5-81] |
64 [45–90] |
0.03 |
|
Body mass index, kg/m2 |
22 [16–33] |
21 [16–30] |
24 [16–33)] |
0.017 |
|
Hemoglobin, g/dL |
8.9 [5.5-14.3] |
8.2 [5.5-12.6] |
10.7 [7.5-14.3] |
<0.001 |
|
Reticulocyte count, ×103/mm3 |
170 [32–466] |
219 [32–466] |
99 [34–271] |
<0.001 |
|
Plasma creatinine, μmol/L |
55 [27–113] |
48 [27–76] |
65 [51–113] |
<0.001 |
|
mGFR, mL/min/1,73 m2 |
112.5 [29–183] |
119 [65–183] |
98 [29–163] |
<0.002 |
|
GFR >110 mL/min/1,73 m2 |
34 (53.1%) |
28 (68.3%) |
6 (26.1%) |
0,0017 |
|
Urinary albumin/creatinine, mg/mmol |
2.87 [0.07-134] |
4.84 [0.14-80.6] |
0.63 [0.07-134] |
0.005 |
|
No albuminuria (<3 mg/mmol) |
32 (50%) |
16 (39%) |
16 (69.5%) |
|
|
Microalbuminuria |
23 (36%) |
17 (41.5%) |
6 (26.1%) |
|
| Macroalbuminuria (>30 mg/mmol) | 9 (14%) | 8 (19.5%) | 1 (4.3%) | 0 .053 |
Results are expressed as numbers (%) or median [range].
M: male, F: female,
mGFR: glomerular filtration rate measured by iohexol plasma clearance.
* Tests are either Chi-square or Fisher’s exact test for categorical variables or Kruskall-Wallis test (more than two groups) or the Mann–Whitney test (two groups) for continuous variables.