Table 3. Gene Ontology (GO) term enrichment analysis results for differentially expressed genes in HAmCqG8.
| GO level | GO term† | Term domain and name | # hits | p-value‡ |
| Down-regulated genes | ||||
| Molecular function | - | - | ||
| structural molecule activity (GO:0005198) | 163 | 1.08×10−11 | ||
| structural constituent of cuticle (GO:0042302) | 85 | 3.19×10−18 | ||
| Up-regulated genes | ||||
| Biological process (GO:0008150) | 193 | 4.28×10−10 | ||
| metabolic process (GO:0008152) | 139 | 1.02×10−7 | ||
| oxidation-reduction process (GO:0055114) | 38 | 5.39×10−9 | ||
| proteolysis (GO:0006508) | 55 | 2.35×10−16 | ||
| Molecular function (GO:0003674) | 250 | 9.80×10−6 | ||
| Catalytic activity (GO:0003824) | 162 | 2.09×10−13 | ||
| oxidoreductase activity (GO:0016491) | 47 | 1.05×10−10 | ||
| monooxygenase activity (GO:0004497) | 29 | 2.84×10−15 | ||
| hydrolase activity (GO:0016787) | 90 | 1.29×10−12 | ||
| peptidase activity (GO:0008233) | 54 | 2.16×10−14 | ||
| peptidase activity, acting on L-amino acid peptides (GO:0070011) | 52 | 1.99×10−15 | ||
| exopeptidase activity (GO:0008238) | 10 | 4.66×10−5 | ||
| carboxypeptidase activity (GO:0004180) | 7 | 1.03×10−4 | ||
| endopeptidase activity (GO:0004175) | 41 | 1.47×10−12 | ||
| metallopeptidase activity (GO:0008237) | 20 | 6.26×10−10 | ||
| metalloendopeptidase activity (GO:0004222) | 11 | 2.42×10−6 | ||
| serine hydrolase activity (GO:0017171) | 30 | 4.39×10−9 | ||
| serine-type peptidase activity (GO:0008236) | 30 | 4.39×10−9 | ||
| serine-type endopeptidase activity (GO:0004252) | 28 | 1.89×10−8 | ||
| hydrolase activity, acting on glycosyl bonds (GO:0016798) | 15 | 1.23×10−7 | ||
| hydrolase activity, hydrolyzing O-glycosyl compounds (GO:0004553) | 13 | 1.17×10−6 | ||
| Electron carrier activity (GO:0009055) | 28 | 6.65×10−14 | ||
| Binding activity | - | - | ||
| tetrapyrrole binding (GO:0046906) | 32 | 1.55×10−17 | ||
| iron ion binding (GO:0005506) | 33 | 3.19×10−15 | ||
| heme binding (GO:0020037) | 32 | 1.32×10−17 | ||
†
Annotation from the Gene Ontology consortium (version 1.2084; release date: 12:07:2011).
‡
Cumulative hypergeometric p-values for GO terms of genes that were differentially up-regulated in when tested against all genes with expression levels of FPKM >1 using the g: SCS threshold.
GO Terms that do not have values for the number of hits or p-values were not statistically enriched in the functional enrichment analysis, but are included in the table to provide all parenthood connections.