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. 2012 Oct 5;7(10):e46987. doi: 10.1371/journal.pone.0046987

Figure 2. Genetic structure of MESPM1 carrying four resistance genes, ermB, aph(3′)-IIIa, aadE, and cat.

Figure 2

MESPM1 was integrated into and disrupted the sasK gene, which encoded a putative cell-wall anchored surface protein with the LPXTG-motif. The intact sasK gene was present in PVL-positive ST59 CA-MRSA type strain USA1000. Three att sites are in a vertical red line. The region of IS1216V with the transposase gene (tnp) is shaded in blue. Homology regions with E. faecalis pLG2 plasmid (GenBank accession number HQ426665) and S. aureus SAP084A (GenBank accession number GQ900436) are shaded in yellow and purple, respectively. A Greek delta symbol indicates truncated coding sequence.