Table 4. The genotype and allele frequencies of RAGE polymorphisms between chemotherapy responders and non-responders.
Responder | Non-responder | global | adjusted | 95%CI | X2 | Adjusted P | |||||
P | OR | ||||||||||
−374T/A | N | % | N | % | |||||||
TT | 18 | 13.53% | 45 | 16.42% | 0.167 | 1 | |||||
TA | 82 | 61.65% | 182 | 66.42% | 1.13 | 0.61 | 2.06 | 0.15 | 0.7 | ||
AA | 33 | 24.81% | 47 | 17.15% | 1.76 | 0.87 | 3.55 | 2.47 | 0.116 | ||
T | 118 | 44.36% | 272 | 49.64% | 1 | ||||||
A | 148 | 55.64% | 276 | 50.36% | 1.24 | 0.92 | 1.66 | 2 | 0.158 | ||
−429T/C | TT | 27 | 20.30% | 42 | 15.33% | 0.338 | 1 | ||||
TC | 82 | 61.65% | 188 | 68.61% | 0.68 | 0.39 | 1.17 | 1.93 | 0.164 | ||
CC | 24 | 18.05% | 44 | 16.06% | 0.85 | 0.42 | 1.7 | 0.22 | 0.642 | ||
T | 136 | 51.13% | 272 | 49.64% | 1 | ||||||
C | 130 | 48.87% | 276 | 50.36% | 0.94 | 0.7 | 1.26 | 0.16 | 0.69 | ||
82G/S | GG | 53 | 39.85% | 73 | 26.64% | 0.019 | 1 | ||||
GS | 59 | 44.36% | 137 | 50.00% | 0.59 | 0.37 | 0.95 | 4.84 | 0.028 | ||
SS | 21 | 15.79% | 64 | 23.36% | 0.45 | 0.25 | 0.83 | 6.72 | 0.01 | ||
G | 165 | 62.03% | 283 | 51.64% | 1 | ||||||
S | 101 | 37.97% | 265 | 48.36% | 0.65 | 0.48 | 0.88 | 7.81 | 0.005 |